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My favourite genres, out of what you've listed, are hard Sci-Fi (think Xeelee Sequence), Dark Fantasy (Diablo), Steampunk (Thief 2), and Space Opera (most sci-fi vidya).
My favourite combination? Shit, I dunno. Probably hard-ish sci-fi meets space opera, in a glorious mix of EVERYTHING FROM SPACE.
But then, I'm one of those fags you find in vs debate threads, so yeah.